Search on: FAS LIGAND PROTEIN 
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Descriptor English:   Fas Ligand Protein 
Descriptor Spanish:   Proteína Ligando Fas 
Descriptor Portuguese:   Proteína Ligante Fas 
Synonyms English:   Antigens, CD178
CD178 Antigens
Tumor Necrosis Factor Ligand Superfamily Member 6  
Tree Number:   D12.644.276.374.750.249
D12.644.276.972.249
D12.776.395.550.312
D12.776.467.374.750.249
D12.776.467.972.249
D12.776.543.550.312
D23.050.301.264.035.284
D23.101.100.110.283
D23.529.374.750.249
D23.529.972.249
Definition English:   A transmembrane protein belonging to the tumor necrosis factor superfamily that was originally discovered on cells of the lymphoid-myeloid lineage, including activated T-LYMPHOCYTES and NATURAL KILLER CELLS. It plays an important role in immune homeostasis and cell-mediated toxicity by binding to the FAS RECEPTOR and triggering APOPTOSIS. 
History Note English:   2007(1994) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   52293 
Unique Identifier:   D053222 

Occurrence in VHL:
 

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